The Integrated Secure Element (iSE) by Secure-IC acts as a root of trust for Systems-On-Chip (SoC), safeguarding the main system processor via advanced security measures such as secure boot processes, anti-tampering mechanisms, and key isolation protocols. Embedded within SoCs, iSE offers a fortified layer of protection that significantly exceeds traditional executing environments by isolating functions and ensuring robust defense against diverse cyber threats. Suitable for a wide range of applications from IoT devices to automotive systems, the iSE delivers top-tier security features that include updates without downtime, extensive cryptographic operations, and real-time monitoring to pre-emptively block any intrusion attempts. This secure element empowers systems with the ability for self-defense against both physical and digital attacks, making it an essential element of next-generation cybersecurity frameworks.