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The xT CDx is a sophisticated Next Generation Sequencing (NGS)-based diagnostic device aimed specifically at identifying genetic alterations in solid tumors. It encompasses a wide range of detection capabilities including single nucleotide variants, insertions, deletions, and microsatellite instability status across 648 genes. Designed to provide targeted treatment paths, the xT CDx plays a critical role in precision oncology by aligning with therapeutic product labels for companion diagnostics. By leveraging both tumor and matched normal samples, this device's comprehensive approach ensures nuanced insights into tumor biology, enabling more personalized therapy regimens for patients. In addition to cancer profiling, xT CDx enhances the accuracy of somatic alteration identification by utilizing a tumor + normal match methodology, minimizing false positives and improving therapy targeting efficiencies. Through its advanced NGS platform, xT CDx is integral to Tempus Labs' drive to enhance personalized cancer care.
The Tempus xT CDx is an innovative NGS-based in vitro diagnostic tool developed to aid in the detection of genetic variations within solid tumors. Offering a comprehensive analysis of 648 genes, it detects a range of genetic alterations such as substitutions, insertions, deletions, and microsatellite instability. The device serves as a companion diagnostic to identify patients who may benefit from targeted therapies and offers a deeper understanding of tumor mutation profiles. This test requires both tumor tissue and normal DNA samples, ensuring accurate detection of somatic mutations and facilitating personalized cancer treatment. Furthermore, by comparing tumor DNA with non-cancerous DNA, xT CDx provides a more precise analysis, reducing false-positive results and identifying actionable mutations for guiding therapy decisions.
Intel expands its foundry ecosystem with alliances with TSMC, UMC, and Taiwanese tech partners, marking a major transformation for the firm's production strategy. Read more
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