Secure OTP is a cutting-edge non-volatile memory solution designed to safeguard key, data, and secret storage with enhanced protection against hardware attacks. It features a combination of physical macros and digital RTL, offering robust anti-tamper and integrated protection mechanisms. This solution is specifically architected for integration in CMOS technologies and is compatible across numerous IC and ASIC applications. By incorporating a 1024-bit PUF for scrambling and I/O shuffling, Secure OTP significantly elevates stored data security, effectively making it tamperproof. As digital security challenges mount, Secure OTP provides a modernized answer, ensuring the safekeeping of critical information across its lifecycle. Its adoption addresses prevalent security gaps in legacy e-fuse solutions and is instrumental in extending robust defense systems within SoC environments, acting as a cornerstone for comprehensive hardware security strategies.